I started writing this blog in October of 2018. I started writing for a few reasons. First, as a more researched voice in a sea of fear mongering half truths on social media. Second, as a way to document my experience in a clinical trial. Third, as a place to talk about the clinical trials occurring in the celiac community.

In 2018 and 2019, I thought a cure was imminent. Between 2020 and 2023, I’ve been excited about drugs and then have to patiently wait for them. In 2020 organizations like Beyond Celiac and the Celiac Disease Foundation began predicting a cure for celiac disease within 10 years.

At the end of 2024, we have a drug on the cusp of starting Phase 3 trials. Latiglutenase is a drug that is only for celiac patients that still have positive celiac blood tests after a year on a gluten free diet. We have two promising drugs TAK-101 and TAK-062 that are close to finishing Phase 2 trials and will be entering Phase 3 trials in 2025.

Studies are showing that celiac disease is often under diagnosed. Mass screenings can help pick up celiac cases that would have otherwise not been found. I’m a little jaded about this one, so I will just leave that fact here for now.

The triple positive diagnosis criteria is starting to become standard across the US, which is great for everyone involved. Less expensive and invasive diagnosis criteria is how more people are diagnosed appropriately.

At the end of 2024, I am starting to see the writing on the wall. I think a treatment, at least for protection from cross contamination, is on its way. I think a cure, meaning return to a gluten containing diet, is also year or two behind the treatment.

Let me know what you think….